|Year||Events in Nagasaki||Events in Japan and Abroad|
|1603||Tokugawa Ieyasu establishes a Shogunate in Edo.|
|1604||Raw silk import allotment system is adopted.|
|1605||Nagasaki is placed under the direct jurisdiction of the Shogunate.|
|1609||The Dutch East India Company establishes a factory (trading post) at Hirado.||The Netherlands wins independence from Spain.|
|1612||Christianity is banned in Nagasaki.|
|1613||The English East India Company establishes a factory (trading post) at Hirado.||A national ban on Christianity is enforced.|
|1614||Silk Allotment Center is established in Nagasaki.||Winter siege of Osaka.|
|1615||Summer siege of Osaka.|
|1616||Trade with countries other than China is confined to Hirado and Nagasaki.|
|1623||The English East India Company Hirado Factory closes.|
|1633||Unauthorized overseas travel is banned |
(first national seclusion edict).
|1634||Construction of Dejima commenced. Spectacles Bridge is built.||All overseas travel is banned |
(second national seclusion edict).
|1635||Chinese ships are confined to Nagasaki.
||Complete ban on exit and entry of Japanese from Japan.|
Complete ban on exit and entry of Japanese from Japan.
The construction of large ships is banned
(third national seclusion edict).
|1636||Dejima reaches completion.||Portuguese are confined to Dejima |
(fourth national seclusion edict).
|1637||The Shimabara-Amakusa Uprising erupts and is quashed the following year.|
|1639||Portuguese are expelled from Japan|
(fifth national seclusion edict)
|1641||The Dutch East India Company Hirado Factory is moved to Dejima.||Policy of national seclusion is completed.|
|1649||German surgeon Casper Schamberger arrives at Dejima.|
|1650||Dutch envoy participates in the journey of tribute to Edo.|
|1662||A shop selling Imari porcelain opens on Dejima.|
|1673||British ship Return enters Nagasaki Harbor seeking trade but is repulsed.|
|1678||A new bridge is built to connect Dejima to the town of Nagasaki.|
|1689||Chinese Quarter reaches completion.|
|1690||German physician Engelbert Kaempfer arrives at Dejima.|
|1696||Merchandise warehouses are constructed.|
|1698||Nagasaki Trade Guild is established.|
|1699||Sea gate is constructed on the western side of Dejima.|
|1707||Water pipes are installed at Dejima.|
|1715||The New Shōtoku Edict is promulgated.|
|1716||Kyōhō Reforms are introduced by the Tokugawa Shogunate.|
|1720||Tokugawa Shogunate lifts the ban on Western studies.|
|1774||Kaitai Shinsho (New Book on Anatomy) is published.|
|1776||United States of America declares independence.|
|1790||The Dutch journey of tribute to Edo is changed to once every four years.|
|1798||Fire ravages Dejima|
|1804||Russian envoy N.P. Lezanov visits Nagasaki.|
|1808||British ship Phaeton visits Nagasaki disguised as a Dutch ship.|
|1809||Chief Factor’s Quarters reach completion.|
|1810||France annexes the Netherlands.|
|1815||Kingdom of the Netherlands declares independence.|
|1823||German physician P.F. von Siebold arrives at Dejima.|
|1824||Siebold establishes the Narutaki Medical School.|
|1826||Siebold erects a monument to Kaempfer and Thunberg in the Dejima herb garden.|
|1828||Siebold is charged with attempting export banned items (Siebold Incident). |
|1840||First Opium War (until 1842).|
|1841||Tenpo Reforms are introduced by the Tokugawa Shogunate (until 1843).|
|1850||The last Dutch journey of tribute to Edo is conducted.|
|1853||Russian envoy Efimi Putiatin visits Nagasaki.||American Commodore Matthew Perry enters Uraga Bay.|
|1854||Japanese-British Treaty of Amity is signed in Nagasaki.|
Ports of Nagasaki and Hakodate are opened to British ships.
|1855||Japanese-Dutch Treaty of Amity is signed in Nagasaki.|
Naval Training Institute is founded.
|1857||Dutch physician J.L.C.Pompe van Meerdervoort arrives in Nagasaki.|
Medical Training Institute is founded.
|1858||the Ansei Five-Power Treaties|
|1859||The Dejima Dutch Factory is abolished and converted into a consulate.|
|1861||Parts of the Dejima periphery are reclaimed from the harbor.||American Civil War.|
|1862||Nagasaki Foreign Settlement reaches completion.|
|1864||Part of the western side of Dejima is reclaimed from the harbor.|
|1866||Dejima is absorbed into the Nagasaki Foreign Settlement.|
|1867||Southern side of Dejima is reclaimed from the harbor to make a promenade.||Tokugawa Shogunate collapses.|